Contents: Preface. 1. The concept of gene. 2.
Fundamentals of proteomics. 3.
Genome structure and operating systems. 4.
Pairwise genomic sequence alignments. 5.
Bioinformatics of DNA microarrays. 6.
Microarray regression approaches. 7.
DNA arrays and gene expression. 8.
Gene expression profiling. 9.
Expressed sequence Tag (EST) databases. 10.
Protein structure prediction. 11.
RNA secondary structure prediction. 12.
Algorithms of Hidden Markov models. 13.
Sequencing of human genome. 14.
G protein-coupled receptors. 15.
Visualisation of biological structures. 16.
Proteome analysis. 17.
Capabilities of proteomics laboratory. 18.
Applications of molecular phylogenetics. 19.
Essentials of medical genomics. Bibliography.
Index. "Bioinformatics is a set of enabling technologies responsible for the annotation, storage, analysis and search/retrieval of nucleic acid sequence, protein sequence and structural information.
This includes integration of the information on the sequences and structures of nucleic acids and proteins into databases such as EMBL, as well as methods to access, search, model and analyse this information. Bioinformatics provides